Phytochemical Screening, Traditional Uses, Pharmacology, Dosing Limit, and Metallic Nanotherapeutics Updates of Tephrosia purpurea Linn.: An Investigation

Abstract

ABSTRACT Rather than relying on synthetic chemicals, herbal medicine employs natural substances found in plants. Natural substances have less potential for adverse effects; hence, these treatments are preferred. Tephrosia purpurea Linn., or sharapunkha in Sanskrit, is a suberect, perennial herb that is extremely branching and herbaceous and extensively cultivated in India. T. purpurea Linn. has been used extensively in conventional medicine for centuries. Both the whole plant and individual portions of the plant have medicinal uses in Ayurvedic practice. Antiulcer, antimicrobial, antibacterial, antiviral, antiasthmatic, hepatoprotective, antihyperglycemic, antihyperlipidemic, antioxidant, wound healing, immunomodulatory, and anti-allergic properties have all been observed in pharmacological tests of T. purpurea Linn. A wide range of phytochemicals with potential medical applications have been identified in the plant. The whole plant contains various phytoconstituents such as Isolonchocarpin, pongamol, Lanceolatin A, Lanceolatin B, Karanjin, Kanjone, and β-sitosterolis. T. purpurea has been the subject of numerous phytochemical analyses, which have uncovered the existence of a wide range of photoactive components. Metal nanoparticles are used in many research areas, such as those that study bacteria, viruses, diagnostics, cancer treatment, and targeted drug delivery. This is because metal nanoparticles (NPs) have unique physical properties and chemical reactions. This article offers a thorough examination of the plant T. purpurea Linn. pharmacology and phytochemistry, as well as conceptual information on the plant’s metallic NPs.