Not so Narrow Escape-a Case Report on Symptomatic HIV-1 CNS Escape Presenting as Progressive Multifocal Leukoencephalopathy-Reference-Cited by-同舟云学术

Not so Narrow Escape-a Case Report on Symptomatic HIV-1 CNS Escape Presenting as Progressive Multifocal Leukoencephalopathy

Published:2023-07 Issue:3 Volume:1 Page:274-276
ISSN:2950-4392
Container-title:Journal of Clinical Infectious Disease Society
language:en
Short-container-title:

Author:

Kuruvilla Dawn¹,Parasrampuria Sakshi¹,Abraham O. Cherian¹,Jasper Anitha²

Affiliation:

1. Department of Medicine, Vellore, Tamil Nadu, India

2. Department of Radiology, Christian Medical College, Vellore, Tamil Nadu, India

Abstract

Abstract Human immunodeficiency virus (HIV) can rarely cause symptomatic central nervous system (CNS) escape as a neurological complication. It is characterized by discordant viral replication in the CNS with adequately suppressed viral load in the serum and can have myriad presentations. We describe an HIV-infected man, nonadherent to antiretroviral therapy, who presented to us with multifocal brain involvement of subcortical white matter and meninges, with the compartmentalization of a drug-resistant strain of HIV within the cerebrospinal fluid.

Publisher

Medknow

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