A Comparative Study of Serum Butyric Acid in Subjects with Tongue Cancer

Author:

Suhasini P. C.1,Shetty Shilpa S.2,Shetty Vijith Vittal3,Bhat Vadisha4,Roopashree P. G.1,Kumari N. Suchetha1

Affiliation:

1. Department of Biochemistry, KS Hegde Medical Academy, NITTE (Deemed to be University), Mangalore, India

2. Department of Cellomics, Lipidomics and Molecular Genetics Division, Central Research Laboratory, KS Hegde Medical Academy, NITTE (Deemed to be University), Mangalore, India

3. Department of Oncology, KS Hegde Medical Academy, NITTE (Deemed to be University), Mangalore, India

4. Department of ENT, KS Hegde Medical Academy, NITTE (Deemed to be University), Mangalore, India

Abstract

Abstract Aim: The aim of the study was to study the level of butyric acid in tongue cancer subjects. Materials and Methods: Thirty controls and 30 tongue cancer subjects were recruited for the study. Serum butyric acid levels were estimated using ELISA kits. Statistical analyses were done using SPSS vs 22. The Mann–Whitney U and Kruskal–Wallis tests were used. P ≤ 0.05 was considered statistically significant. Results: Butyric acid levels were significantly higher in control subjects when compared to case subjects. Conclusion: Butyric acid could be used as a potential anticancer agent in tongue cancer treatment.

Publisher

Medknow

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