Cell-free DNA as a Novel Diagnostic Biomarker for Periodontitis

Author:

Kulkarni Pranav1,Dodwad Vidya1,Bhosale Nishita1,Pharne Pooja1,Bhatt Niket1

Affiliation:

1. Department of Periodontology, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Pune, Maharashtra, India

Abstract

Periodontitis, a common inflammatory disease affecting the periodontal tissue, poses diagnostic and management challenges. Conventional methods are not capable of assessing disease activity or identifying individuals who are prone to progression. Biomarkers, measurable substances that indicate the presence, severity, or progression of disease, offer a promising approach to diagnosing periodontitis. Recent discoveries in molecular diagnostics have prompted the search for novel biomarkers, including cell-free DNA (cfDNA). This review article gives an insight into current knowledge regarding the use of cfDNA as a diagnostic marker in periodontal disease diagnosis.

Publisher

Medknow

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