Disseminated Intravascular Coagulation during a Course of Miliary Tuberculosis with Acute Respiratory Distress Syndrome

Author:

Sharma Kapil1,Jaryal Ajay1,Sharma Sumita2,Rana Lokesh3

Affiliation:

1. Department of General Medicine, AIIMS, Bilaspur, Himachal Pradesh, India

2. Department of Biochemistry, AIIMS, Bilaspur, Himachal Pradesh, India

3. Department of Radiology, AIIMS, Bilaspur, Himachal Pradesh, India

Abstract

Abstract Miliary tuberculosis (TB) can occasionally lead to acute respiratory distress syndrome (ARDS) and disseminated intravascular coagulation (DIC). In this case report, we present the case of an 18-year-old male who was diagnosed with miliary TB based on miliary shadows on X-ray and computed tomography of the chest, as well as positivity for mycobacterium TB in endotracheal aspirate by cartridge-based nucleic acid amplification. The patient’s hospital stay was complicated by ARDS and DIC, which was successfully managed with ventilatory support, administration of antitubercular treatment, systemic corticosteroids, and blood products.

Publisher

Medknow

Reference9 articles.

1. Miliary tuberculosis:A new look at an old foe;Sharma;J Clin Tuberc Other Mycobact Dis,2016

2. A case of miliary tuberculosis complicated by disseminated intravascular coagulation and acute respiratory distress syndrome successfully treated with recombinant human soluble thrombomodulin;Shiraishi;Kekkaku,2012

3. Tuberculous pneumonia-induced severe ARDS complicated with DIC in a female child:A case of successful treatment;Ngo;BMC Infect Dis,2018

4. Miliary tuberculosis;Mert;Medicine,2017

5. Acute respiratory distress syndrome in disseminated tuberculosis:An uncommon association;Sharma;Int J Tuberc Lung Dis,2016

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