Affiliation:
1. Department of Microbiology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India
Abstract
Abstract
Salmonella enterica serovar Typhi and Paratyphi usually cause enteric fever in humans characterized by fever and gastrointestinal symptoms such as diarrhea. Bacteremia is a constant feature of enteric fever, and occasionally, dissemination of bacilli throughout the body results in the establishment of one or more localized foci of persisting infection. This happens especially in patients with preexisting conditions such as hemoglobinopathies, previous joint trauma, surgery, connective tissue diseases, lymphoma, diabetes, alcoholism, immunosuppressive state, and extremes of ages. Rarely, these extraintestinal Salmonella infection cases have also been reported in immunocompetent individuals without any obvious predisposing factors. Salmonella osteomyelitis, a rare sequelae of typhoid, may occur as a result of hematogenous seeding of the bone or joints due to a bacteremic episode. It may also spread from nearby areas of infection or penetrating trauma. Timely diagnosis and treatment of this condition are necessary because if left untreated, it can lead to permanent functional deficits later on. We hereby present a case series with brief review of literature on Salmonella osteomyelitis in immunocompetent patients without any known predisposing conditions over a period of 1 year (2017–2018) from a Tertiary Care Teaching Hospital in Uttarakhand, India.
Reference41 articles.
1. Popoff MY, Minor LL. WHO collaborating centre for reference and research on Salmonella. Antigenic Formulas of the Salmonella Serovars. 7th Revision. Paris, France: Institut Pasteur; 1997.
2. Giannella RA. Salmonella. In: Baron S, editor. Medical Microbiology. 4th ed., Ch 21. Galveston (TX); Univ of Texas Medical Branch: 1996.
3. World Health Organization. Typhoid. World Health Organization; 2018. Available from: http://www.who.int/immunization/diseases/typhoid/en/. [Last updated 2018 Sep 11; Last accessed 2018 Sep 20].
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