Squamous cell carcinoma in bladder extrophy

Abstract

AbstractExtrophy of the bladder is a rare congenital anomaly with an incidence of about 1/50000 newborn. Malignant potential of ectopic mucosa is high. Sixty percent of cancers in ectopic bladder occur during fourth and fifth decade of life, majority being adenocarcinoma (95%). Here we report a case of squamous cell carcinoma of ectopic urinary bladder in a 74-year-old male patient. In view of locally advanced disease, he received neoadjuvant chemotherapy with poor response. He underwent total cystectomy with ileal conduit diversion and continues to be alive and disease free at 36 months interval. The case is being reported on account of its rarity. Pertinent literature is being reviewed.