The process of carcinogenesis described by mathematical formulas

Abstract

The paper presents neoplasms as dissipative structures formed de novo in the host organism under conditions far from thermodynamic equilibrium. The neoplastic process has also been described as a form of random ”blastoid regeneration” (Fig. 2), and the use of information theory elements in this process has been shown to be expedient. The dissipative (precancerous) state may regress, or a thermodynamic branch may develop, and from it – as a result of neoplastic transformation – neoplasm, as illustrated in Figure 4, in the form of an ontogenetic ”tree”. Structures dissipative with fluctuating changes can probably create more and more organized formations, and thus the molecular level would explain Darwin’s theory of evolution and selection. Neoplasms are emergent structures created in the creative process and as disordered and unstable systems, they tend to the state of thermodynamic equilibrium, i.e. death. Their death can be accelerated by anti-cancer therapy or they die with the death of the macro-organism.