Use of C-reactive protein as a marker for Lyme disease in Bernese Mountain Dogs – a preliminary study

Author:

PISAREK MARIA,KALINOWSKI MARCIN,OR MEHMET ERMAN,DOKUZEYLÜL BANU,TEODOROWSKI OLIWIER,DENEKA ŁUKASZ,RUTKOWSKA-SZULCZYK MAŁGORZATA,WINIARCZYK STANISŁAW,ADASZEK ŁUKASZ

Abstract

The aim of the study was to determine the correlation between serum C-reactive protein (CRP) levels, the presence of antibodies to B. burgdorferi, and the occurrence of clinical signs of Lyme borreliosis in Bernese Mountain Dogs (BMDs). The study included 54 BMDs divided into three groups. The first group (n = 29) consisted of animals with signs suggestive of Lyme disease and rapid tests showing the presence of antibodies to B. burgdorferi in their serum. The second group (n = 15) included dogs that did not show signs of Lyme disease and had antibodies to spirochetes in their serum. The third group consisted of BMDs (n = 10) that showed no signs of disease and in whose serum no antibodies to B. burgdorferi were detected by rapid tests. Of the 29 dogs in the first group, 18 had elevated CRP levels. These animals showed signs of arthritis and renal failure. After treatment with doxycycline, the clinical signs of the disease disappeared, and the CRP concentration decreased to normal levels in 16 dogs. In the second group, 2 animals had elevated CRP levels, while in the third group, no antibodies to spirochetes were detected in the serum of any of the dogs, and CRP levels remained within the physiologically normal range. Our own observations indicate that C-reactive protein is a promising marker for monitoring the effectiveness of Lyme disease therapy in BMDs, as well as for distinguishing asymptomatic positive seroreagents from dogs of this breed that are actually suffering from the disease. However, to confirm its usefulness, further research is needed on representatives of this breed, especially those suffering from a chronic form of the disease.

Publisher

Medycyna Weterynaryjna - Redakcja

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3