Surgical Treatment of Renal Carcinoma with Atrial Tumor Thrombus Avoiding Cardiopulmonary Bypass: Step-by-Step Description

Author:

Guglielmo Nicola1,Melandro Fabio1,Montalto Gioacchino1,Poli Luca1,Pietra Fatima Della1,Rossi Massimo1,Mazzesi Giuseppe1,Berloco Pasquale1

Affiliation:

1. Department of General Surgery and Human Organs Transplant, “Sapienza” University of Rome, Rome - Italy

Abstract

Tumor thrombus in the inferior vena cava (IVC) occurs in 4–10% of patients with renal cell carcinoma (RCC) and poses a challenge for the surgical team. Because there is no systemic therapy available to significantly reduce tumor burden, surgical intervention is the only treatment. However, the surgical approach is associated with significant morbidity and mortality. When the thrombus extends above the diaphragm, the use of cardiopulmonary bypass (CPB) and accompanying deep hypothermic circulatory arrest (DHCA) has usually been advocated. However, complications inherent to CPB and DHCA, such as coagulopathy and central nervous system complications, have led us to search for an alternative surgical approach to these tumors. The purpose of this study is to describe the surgical technique used in five patients with large RCC with tumor thrombus extending into the supradiaphragmatic IVC and Right atrium (RA), Right atrium, who underwent extensive resection without CPB and DHCA.

Publisher

SAGE Publications

Subject

General Medicine

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