Concise Survey of Staphylococcus Aureus Virulence Factors that Promote Adhesion and Damage to Peri-Implant Tissues-Reference-Cited by-同舟云学术

Concise Survey of Staphylococcus Aureus Virulence Factors that Promote Adhesion and Damage to Peri-Implant Tissues

Published:2011-09 Issue:9 Volume:34 Page:771-780
ISSN:0391-3988
Container-title:The International Journal of Artificial Organs
language:en
Short-container-title:Int J Artif Organs

Author:

Arciola Carla Renata¹²,Visai Livia³⁴⁵,Testoni Francesca¹,Arciola Susanna¹⁶,Campoccia Davide¹,Speziale Pietro³,Montanaro Lucio¹²

Affiliation:

1. Research Unit on Implant Infections, Rizzoli Orthopaedic Institute, Bologna - Italy

2. Department of Experimental Pathology, University of Bologna, Bologna - Italy

3. Department of Biochemistry, University of Pavia, Pavia - Italy

4. Center for Tissue Engineering (C.I.T.), University of Pavia; Salvatore Maugeri Foundation IRCCS, Pavia - Italy

5. International Center for Studies and Research in Biomedicine (I.C.B.) - Luxembourg

6. Internal Medicine and Emergency Room, Ospedale Buon Consiglio Fatebenefratelli, Naples - Italy

Abstract

Staphylococcus aureus is the leading cause of infection in orthopedic implants and of osteomyelitis consequent to it. Here we focus on the wide array of virulence factors that endow S. aureus with its abilities to colonize peri-prosthesis tissues and to attack and damage them. Following an infective strategy orchestrated by agr locus, Staphylococcus aureus first deploys virulence factors for adhesion to the prosthesis and peri-prosthesis tissues and then launches its attack by delivering destructive factors.

Publisher

SAGE Publications

Subject

Biomedical Engineering,Biomaterials,General Medicine,Medicine (miscellaneous),Bioengineering

Link

http://journals.sagepub.com/doi/pdf/10.5301/ijao.5000046

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