Characterization of the Mechanical and Biological Properties of a New Alumina Scaffold

Abstract

Purpose In this work, an alumina scaffold was produced through a new method to be used in a near future as a bone substitute. Methods In vitro and in vivo studies were performed in order to characterize the mechanical and biological properties of the scaffold. Results The results obtained showed that this scaffold has high mechanical resistance and a porous surface that allows human osteoblast cells to adhere and proliferate. The in vivo studies revealed no systemic reaction. Conclusions The alumina scaffold produced herein has the mechanical and biological properties that are compatible with its application in bone therapy.