Primary Large Cell Neuroendocrine Carcinoma of the Renal Pelvis: A Case Report

Author:

Palumbo Carlotta1,Talso Michele1,Dell'Orto Paolo Guido1,Cozzi Gabriele1,De Lorenzis Elisa1,Conti Andrea1,Maggioni Marco2,Cesare Rocco Bernardo Maria1,Maggioni Augusto1,Rocco Francesco1

Affiliation:

1. Department of Urology, University of Milan, IRCCS Ca’ Granda Ospedale Maggiore Policlinico di Milano, Milan - Italy

2. Department of Anatomopathology, University of Milan, IRCCS Ca’ Granda Ospedale Maggiore Policlinico di Milano, Milan - Italy

Abstract

We report a case of primary large cell neuroendocrine carcinoma of the renal pelvis, diagnosed in a 79-year-old man. The abdominal computed tomography showed a solid, vegetant lesion in the left renal pelvis, conditioning marked hydronephrosis. The patient underwent radical nephroureterectomy. The histological examination showed a large cell neuroendocrine carcinoma associated with a high-grade urothelial carcinoma, with local invasion (pT3). Large cell renal neuroendocrine carcinomas are rare tumors with an aggressive course and a bad prognosis. At present, only five cases were reported in literature.

Publisher

SAGE Publications

Subject

General Medicine

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