Adhesion of Biocompatible and Biodegradable Micropatterned Surfaces-Reference-Cited by-同舟云学术

Adhesion of Biocompatible and Biodegradable Micropatterned Surfaces

Published:2011-01-03 Issue:2 Volume:34 Page:180-184
ISSN:0391-3988
Container-title:The International Journal of Artificial Organs
language:en
Short-container-title:Int J Artif Organs

Author:

Kaiser Jessica S.¹,Kamperman Marleen¹²,De Souza Emerson J.¹³,Schick Bernhard⁴,Arzt Eduard¹

Affiliation:

1. Functional Surfaces Group, Campus D2 2, INM - Leibniz Institute for New Materials, Saarbrücken - Germany

2. Laboratory of Physical Chemistry and Colloid Science, Wageningen University, Wageningen - The Netherlands

3. Mechanical Science and Engineering, University of Illinois, Urbana, IL - USA

4. Hospital Homburg, Department of Otorhinolaryngology, Homburg - Germany

Abstract

We studied the effects of pillar dimensions and stiffness of biocompatible and biodegradable micropatterned surfaces on adhesion on different compliant substrates. The micropatterned adhesives were based on biocompatible polydimethylsiloxane (PDMS) and biodegradable poly(lactic-co-glycolic) acid (PLGA) polymer systems. Micropatterned and non-patterned compliant PDMS did not show significant differences in adhesion on compliant mice ear skin or on gelatin-glycerin model substrates. However, adhesion measurements for micropatterned stiff PLGA on compliant gelatin-glycerin model substrates showed significant enhancement in pull-off strengths compared to non-patterned controls.

Publisher

SAGE Publications

Subject

Biomedical Engineering,Biomaterials,General Medicine,Medicine (miscellaneous),Bioengineering

Link

http://journals.sagepub.com/doi/pdf/10.5301/IJAO.2011.6393

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