Thioredoxin reductase inhibitor auranofin prevents membrane transport of diphtheria toxin into the cytosol and protects human cells from intoxication-Reference-Cited by-同舟云学术

Thioredoxin reductase inhibitor auranofin prevents membrane transport of diphtheria toxin into the cytosol and protects human cells from intoxication

Published:2016-06 Issue: Volume:116 Page:23-28
ISSN:0041-0101
Container-title:Toxicon
language:en
Short-container-title:Toxicon

Author:

Schnell Leonie,Dmochewitz-Kück Lydia,Feigl Peter,Montecucco Cesare,Barth Holger

Funder

Deutsche Forschungsgemeinschaft DFG

International Graduate School in Molecular Medicine Ulm

Publisher

Elsevier BV

Subject

Toxicology

Reference42 articles.

1. Membrane translocation of diphtheria toxin A-fragment: role of carboxy-terminal region;Ariansen;Biochemistry,1993

2. Reductive activation of ricin and ricin A-chain immunotoxins by protein disulfide isomerase and thioredoxin reductase;Bellisola;Biochem. Pharmacol.,2004

3. Fused polycationic peptide mediates delivery of diphtheria toxin A chain to the cytosol in the presence of anthrax protective antigen;Blanke;Proc. Natl. Acad. Sci. U. S. A.,1996

4. The cytotoxic necrotizing factors from Yersinia pseudotuberculosis and from Escherichia coli bind to different cellular receptors but take the same route to the cytosol;Blumenthal;Infect. Immun.,2007

5. The mechanisms of action of disease-modifying antirheumatic drugs: a review with emphasis on macrophage signal transduction and the induction of proinflammatory cytokines;Bondeson;Gen. Pharmacol.,1997

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