Apparent marked reduction in early antivenom reactions compared to historical controls: Was it prophylaxis or method of administration?

Author:

Caron Elena J.,Manock Stephen R.,Maudlin Jeffrey,Koleski Jerome,Theakston R. David G.,Warrell David A.,Smalligan Roger D.

Publisher

Elsevier BV

Subject

Toxicology

Reference25 articles.

1. Clinical features and severity grading of anaphylaxis;Brown;J Allergy Clin. Immunol.,2004

2. Randomized comparative trial of three antivenoms in the treatment of envenoming by lance-headed vipers (Bothrops jararaca) in Sao Paulo, Brazil;Cardoso;Q. J. Med.,1993

3. Safety of subcutaneous adrenaline as prophylaxis against acute adverse reactions to anti-venom serum in snakebite;Dassanayake;Ceylon Med. J.,2002

4. de Silva, H.A., Pathmeswaran, A., Jayamanne, S., Ariyasena, H., Ratnatilaka, G.A., Kalupahana, R., Uluwatte, W., Ranasinha, C.D., Armitage, J., Aronson, J.K., Lalloo, D.G., de Silva, H.J., 2008. Prevention of acute adverse reactions to snake antivenom after snakebite: multi-centre, randomized, controlled clinical trial. In: Presented at the Global Issues in Clinical Toxinology 2008 Conference, 23–28 November 2008, University of Melbourne, Australia.

5. Sequential, randomised and double-blind trial of promethazine prophylaxis against early anaphylactic reactions to antivenom for Bothrops snakebites;Fan;Br. Med. J.,1999

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