Enhancing snakebite management: The role of small molecule therapeutics in complementing antivenom strategies

Author:

Silva Glória Maria da,Chowdhury Abhinandan

Funder

FAPEMIG

Publisher

Elsevier BV

Reference181 articles.

1. TRUE-1: trial of Repurposed Unithiol for snakebite Envenoming phase 1 (safety, tolerability, pharmacokinetics and pharmacodynamics in healthy Kenyan adults);Abouyannis;Wellcome Open Res,2022

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3. The paraspecific neutralisation of snake venom induced coagulopathy by antivenoms;Ainsworth;Commun. Biol.,2018

4. A therapeutic combination of two small molecule toxin inhibitors provides broad preclinical efficacy against viper snakebite;Albulescu;Nat. Commun.,2020

5. Preclinical validation of a repurposed metal chelator as an early-intervention therapeutic for hemotoxic snakebite;Albulescu;Sci. Transl. Med.,2020

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