Protective effect of ginsenoside Rb1 against aconitine cardiotoxicity studied by myocardial injury, action potential, and calcium signaling

Author:

Zhang Cuihan,Hou Huan,Shen Changhong,Ran Qian,Cheng Fang,Yao Ziqing,Zhang Ruoqi,Peng Cheng

Funder

Chengdu University of TCM

Publisher

Elsevier BV

Reference30 articles.

1. Cardiac excitation-contraction coupling;Bers;Nat. Rev. Mol. Cell Biol.,2002

2. Protective effect of berberine on aconiteinduced myocardial injury and the associated mechanisms;Chen;Mol. Med. Rep.,2018

3. Disruption of the intracellular Ca2+ homeostasis in the cardiac excitation-contraction coupling is a crucial mechanism of arrhythmic toxicity in aconitine-induced cardiomyocytes;Fu;Biochem. Biophys. Res. Commun.,2007

4. Aconitine induces apoptosis in H9c2 cardiac cells via mitochondriamediated pathway;Gao;Mol. Med. Rep.,2018

5. Proteomic analysis reveals ginsenoside Rb1 attenuates myocardial ischemia/reperfusion injury through inhibiting ROS production from mitochondrial complex I;Jiang;Theranostics,2021

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