Development and evaluation of a human CD47/HER2 bispecific antibody for Trastuzumab-resistant breast cancer immunotherapy

Author:

Zhang Binglei,Shi Jianxiang,Shi Xiaojing,Xu Xiaolu,Gao Le,Li Song,Liu Mengmeng,Gao Mengya,Jin Shuiling,Zhou Jian,Fan Dandan,Wang Fang,Ji Zhenyu,Bian Zhilei,Song Yongping,Tian Wenzhi,Zheng Yichao,Xu Linping,Li Wei

Funder

National Natural Science Foundation of China

Publisher

Elsevier BV

Reference72 articles.

1. CD47 blockade by Hu5F9-G4 and rituximab in Non-Hodgkin’s lymphoma;Advani;N. Engl. J. Med.,2018

2. Activity and tolerabilty of the first-in-class anti-CD47 antibody Hu5F9-G4 with rituximab tolerated in relapsed/refractory non-Hodgkin lymphoma: Initial phase 1b/2 results;Advani;J. Clin. Oncol.,2018

3. A phase 1 study of TTI-621, a novel immune checkpoint inhibitor targeting CD47, in patients with relapsed or refractory hematologic malignancies;Ansell;Blood,2016

4. Phase I study of the CD47 blocker TTI-621 in patients with relapsed or refractory hematologic malignancies;Ansell;Clin. Cancer Res.,2021

5. A vaccine targeting resistant tumours by dual T cell plus NK cell attack;Badrinath;Nature,2022

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