Association between the perturbation of bile acid homeostasis and valproic acid-induced hepatotoxicity

Author:

Chen Yanan,Zhou Jingkai,Xu ShansenORCID,Liu Mei,Wang Minglu,Ma Yiyi,Zhao Mingming,Wang Zhanyou,Guo Yingjie,Zhao Limei

Funder

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference42 articles.

1. Valproic acid and epilepsy: from molecular mechanisms to clinical evidences;Romoli;Curr. Neuropharmacol.,2018

2. A phase 2 study of concurrent radiation therapy, temozolomide, and the histone deacetylase inhibitor valproic acid for patients with glioblastoma;Krauze;Int. J. Radiat. Oncol. Biol. Phys.,2015

3. Valproic acid (VPA) in patients with refractory advanced cancer: a dose escalating phase I clinical trial;Atmaca;Br. J. Cancer,2007

4. Adverse drug reactions induced by valproic acid;Nanau;Clin. Biochem.,2013

5. Biotransformation and pharmacokinetics in the rhesus monkey of 2-n-propyl-4-pentenoic acid, a toxic metabolite of valproic acid;Rettenmeier;Drug Metab. Dispos.,1986

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