Vitamin K3 chloro derivative (VKT-2) inhibits HDAC6, activates autophagy and apoptosis, and inhibits aggresome formation in hepatocellular carcinoma cells

Author:

Dawood Mona,Hegazy Mohamed-Elamir F.,Elbadawi Mohamed,Fleischer Edmond,Klinger Anette,Bringmann Gerhard,Kuntner Claudia,Shan Letian,Efferth Thomas

Funder

Ministry of Higher Education and Scientific Research and of the Al-Neelain University, Khartoum, Sudan

International Office, Johannes Gutenberg University

Alexander von Humboldt Foundation

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference74 articles.

1. Epigenetics in cancer therapy and nanomedicine;Roberti;Clin. Epigenetics,2019

2. Targeting epigenetics in cancer;Bennett;Annu. Rev. Pharmacol. Toxicol.,2018

3. Chimeric HDAC inhibitors: Comprehensive review on the HDAC-based strategies developed to combat cancer;Hesham;Med. Res. Rev.,2018

4. Development of a novel histone deacetylase-targeted near-infrared probe for hepatocellular carcinoma imaging and fluorescence image-guided surgery;Tang;Mol. Imaging Biol.,2019

5. Downregulation of HDAC6 promotes angiogenesis in hepatocellular carcinoma cells and predicts poor prognosis in liver transplantation patients;Lv;Mol. Carcinog.,2016

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