Ligand-directed biased agonism at human histamine H3 receptor isoforms across Gαi/o- and β-arrestin2-mediated pathways

Author:

Rahman Sabrina N.,Imhaouran Faissal,Leurs Rob,Christopoulos Arthur,Valant Céline,Langmead Christopher J.ORCID

Funder

NHMRC

Netherlands Organisation for Scientific Research

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference65 articles.

1. Cloning and Functional Expression of the Human Histamine H3 Receptor;Lovenberg;Mol. Pharmacol.,1999

2. Therapeutic potential of histamine H3 receptor agonist for the treatment of obesity and diabetes mellitus;Yoshimoto;PNAS,2006

3. N.L. Lethbridge, 2011. Histamine H3 Receptor Heterogeneity in the Central Nervous System in Aging and Dementia. Durham theses, Durham University.

4. Inhibition of histamine receptor 3 suppresses glioblastoma tumor growth, invasion, and epithelial-to-mesenchymal transition;Lin;Oncotarget,2015

5. Histamine H3 receptor antagonists display antischizophrenic activities in rats treated with MK-801;Mahmood;J. Basic Clin. Physiol. Pharmacol.,2016

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