Rational design of an AKR1C3-resistant analog of PR-104 for enzyme-prodrug therapy-Reference-Cited by-同舟云学术

Rational design of an AKR1C3-resistant analog of PR-104 for enzyme-prodrug therapy

Published:2016-09 Issue: Volume:116 Page:176-187
ISSN:0006-2952
Container-title:Biochemical Pharmacology
language:en
Short-container-title:Biochemical Pharmacology

Author:

Mowday Alexandra M.,Ashoorzadeh Amir,Williams Elsie M.,Copp Janine N.,Silva Shevan,Bull Matthew R.,Abbattista Maria R.,Anderson Robert F.,Flanagan Jack U.,Guise Christopher P.,Ackerley David F.,Smaill Jeff B.,Patterson Adam V.

Funder

Health Research Council of New Zealand

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference45 articles.

1. Bystander or no bystander for gene directed enzyme prodrug therapy;Dachs;Molecules,2009

2. Nitroreductase gene-directed enzyme prodrug therapy: insights and advances toward clinical utility;Williams;Biochem. J.,2015

3. Virus directed enzyme prodrug therapy for ovarian and pancreatic cancer using retrovirally delivered E. coli nitroreductase and CB1954;McNeish;Gene Ther.,1998

4. Gene-directed enzyme prodrug therapy: quantitative bystander cytotoxicity and DNA damage induced by CB1954 in cells expressing bacterial nitroreductase;Friedlos;Gene Ther.,1998

5. Virus-directed enzyme prodrug therapy using CB1954;Grove;Anticancer Drug Des.,1999

Cited by 17 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The Catalysis Mechanism of E. coli Nitroreductase A, a Candidate for Gene-Directed Prodrug Therapy: Potentiometric and Substrate Specificity Studies;International Journal of Molecular Sciences;2024-04-17

2. Clostridium Bacteria: Harnessing Tumour Necrosis for Targeted Gene Delivery;Molecular Diagnosis & Therapy;2024-02-02

3. Design and Biological Evaluation of Piperazine-Bearing Nitrobenzamide Hypoxia/GDEPT Prodrugs: The Discovery of CP-506;ACS Medicinal Chemistry Letters;2023-10-05

4. Nitroreduction: A Critical Metabolic Pathway for Drugs, Environmental Pollutants, and Explosives;Chemical Research in Toxicology;2022-08-31

5. Bioreductive prodrug PR-104 improves the tumour distribution and titre of the nitroreductase-armed oncolytic adenovirus ONYX-411NTR leading to therapeutic benefit;Cancer Gene Therapy;2021-11-26