Genistein and/or sulfasalazine ameliorate acetic acid-induced ulcerative colitis in rats via modulating INF-γ/JAK1/STAT1/IRF-1, TLR-4/NF-κB/IL-6, and JAK2/STAT3/COX-2 crosstalk

Author:

Elhefnawy Esraa A.ORCID,Zaki Hala F.,El Maraghy Nabila N.,Ahmed Kawkab A.,Abd El-Haleim Enas A.

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference92 articles.

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2. Mechanisms of disease: pathogenesis of Crohn’s disease and ulcerative colitis, Nature Clinical Practice;Sartor;Gastroenterol. Hepatol.,2006

3. A comprehensive review and update on ulcerative colitis;Gajendran;Dis. Mon.,2019

4. Preventive empagliflozin activity on acute acetic acid-induced ulcerative colitis in rats via modulation of SIRT-1/PI3K/AKT pathway and improving colon barrier;Zaghloul;Environ. Toxicol. Pharmacol.,2022

5. Second European evidence-based consensus on the diagnosis and management of ulcerative colitis Part 3: Special situations;van Assche;J. Crohn’s Colitis,2012

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