Towards a thermodynamic definition of efficacy in partial agonism: The thermodynamics of efficacy and ligand proton transfer in a G protein-coupled receptor of the rhodopsin class

Author:

Broadley Kenneth J.,Sykes Shane C.,Davies Robin H.

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference36 articles.

1. Towards a thermodynamic definition in partial agonism;Broadley;Biochem Pharmacol,2010

2. Operational models of pharmacological agonism;Black;Proc R Soc Lond B,1983

3. Fundamental difference between the molecular interactions of agonists and antagonists with the beta-adrenergic receptor;Weiland;Nature,1979

4. Thermodynamics of agonist and antagonist interactions with mammalian beta-adrenergic receptors;Weiland;Mol Pharmacol,1980

5. Thermodynamic properties of agonist interactions with the beta-adrenergic receptor-coupled adenylate cyclase system. I: high and low affinity states of agonist binding to membrane-bound beta-adrenergic receptors;Contreras;J Pharm Exp Ther,1986

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