Integration of temporal single cell cellular stress response activity with logic-ODE modeling reveals activation of ATF4-CHOP axis as a critical predictor of drug-induced liver injury-Reference-Cited by-同舟云学术

Integration of temporal single cell cellular stress response activity with logic-ODE modeling reveals activation of ATF4-CHOP axis as a critical predictor of drug-induced liver injury

Published:2021-08 Issue: Volume:190 Page:114591
ISSN:0006-2952
Container-title:Biochemical Pharmacology
language:en
Short-container-title:Biochemical Pharmacology

Author:

Wijaya Lukas Surya,Trairatphisan Panuwat^ORCID,Gabor Attila,Niemeijer Marije^ORCID,Keet Jason,Alcalà Morera Ariadna,Snijders Kirsten E.,Wink Steven,Yang Huan^ORCID,Schildknecht Stefan^ORCID,Stevens James L.,Bouwman Peter^ORCID,Kamp Hennicke^ORCID,Hengstler Jan,Beltman Joost^ORCID,Leist Marcel^ORCID,Le Dévédec Sylvia,Saez-Rodriguez Julio,van de Water Bob

Funder

European Commission

Netherlands Organisation for Health Research and Development

Horizon 2020 Framework Programme

Innovative Medicines Initiative

European Federation of Pharmaceutical Industries and Associations

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference54 articles.

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