[3H]OSIP339391, a selective, novel, and high affinity antagonist radioligand for adenosine A2B receptors

Author:

Stewart Mike,Steinig Arno G,Ma Chienling,Song Jian-Ping,McKibben Bryan,Castelhano Arlindo L,MacLennan Stephen J

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference21 articles.

1. Bennett JP. Receptor binding methods. In: Yamamura HI, Enna SJ, Kuhar MJ, editors. Neurotransmitter receptor binding. New York: Raven Press; 1978. p. 57–90.

2. Why are A2B receptors low-affinity receptors? Mutation of Asn273 to TYR increases affinity of human A2B receptor for 2-(1-hexynyl)adenosine;Beukers;Mol. Pharmacol,2000

3. Characterisation of the A2 adenosine receptor labeled by [3H]-NECA in rat striatal membranes;Bruns;Mol. Pharmacol.,1986

4. Selective A1-adenosine receptor antagonists identified using Saccharomyces cerevisiae functional assays;Campbell;Bioorg Med Chem Lett,1999

5. Castelhano AL, McKibben B, Steinig AG. Preparation of pyrrolopyrimidine A2b selective antagonist compounds, method of synthesis and therapeutic use. PCT Int Appl 2003;WO2003053361.

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