Downregulation of PDZK1 by TGF-β1 promotes renal fibrosis via inducing epithelial-mesenchymal transition of renal tubular cells

Author:

Lu Shuanghui,Chen Xiu,Chen Yujia,Zhang Yingqiong,Luo Jun,Jiang Huidi,Fang Luo,Zhou Hui

Funder

Wuhan University School of Medicine

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference51 articles.

1. GBD Chronic Kidney Disease Collaborate, Global, regional, and national burden of chronic kidney disease, 1990-2017: a systematic analysis for the global burden of disease study 2017 [J], Lancet 395 (2020) 709-733.

2. Kidney fibrosis: from mechanisms to therapeutic medicines [J];Huang;Signal Transduct Target Ther,2023

3. TGF-beta: the master regulator of fibrosis [J];Meng;Nat Rev Nephrol,2016

4. A potential role of the renin-angiotensin-aldosterone system in epithelial-to-mesenchymal transition-induced renal abnormalities: Mechanisms and therapeutic implications [J];Balakumar;Pharmacol Res,2019

5. How to inhibit transforming growth factor beta safely in diabetic kidney disease [J];Yang;Curr Opin Nephrol Hypertens,2021

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