AR12 (OSU-03012) suppresses GRP78 expression and inhibits SARS-CoV-2 replication-Reference-Cited by-同舟云学术

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AR12 (OSU-03012) suppresses GRP78 expression and inhibits SARS-CoV-2 replication

Published:2020-12 Issue: Volume:182 Page:114227
ISSN:0006-2952
Container-title:Biochemical Pharmacology
language:en
Short-container-title:Biochemical Pharmacology

Author:

Rayner Jonathan O.,Roberts Rosemary A.,Kim Jin,Poklepovic Andrew,Roberts Jane L.,Booth Laurence,Dent Paul

Funder

NIEHS

Virginia Commonwealth University

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference32 articles.

1. Role of the unfolded protein response, GRP78 and GRP94 in organ homeostasis: UPR AND GRPs REGULATE ORGAN HOMEOSTASIS;Zhu;J. Cell. Physiol.,2015

2. BiP: master regulator of the unfolded protein response and crucial factor in flavivirus biology;Lewy;Yale J Biol Med.,2017

3. OSU-03012 suppresses GRP78/BiP expression that causes PERK-dependent increases in tumor cell killing;Booth;Cancer Biol. Ther.,2012

4. GRP78/BiP/HSPA5/Dna K is a universal therapeutic target for human disease: AR-12 AND VIAGRA;Booth;J. Cell. Physiol.,2015

5. Regulation of OSU-03012 toxicity by ER stress proteins and ER stress-inducing drugs;Booth;Mol. Cancer Ther.,2014

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