The anticancer multi-kinase inhibitor dovitinib also targets topoisomerase I and topoisomerase II-Reference-Cited by-同舟云学术

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The anticancer multi-kinase inhibitor dovitinib also targets topoisomerase I and topoisomerase II

Published:2012-12 Issue:12 Volume:84 Page:1617-1626
ISSN:0006-2952
Container-title:Biochemical Pharmacology
language:en
Short-container-title:Biochemical Pharmacology

Author:

Hasinoff Brian B.,Wu Xing,Nitiss John L.,Kanagasabai Ragu,Yalowich Jack C.

Funder

Canadian Institutes of Health Research

Canada Research Chairs Program

Canada Research Chair in Drug Development

NIH

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference44 articles.

1. Comprehensive analysis of kinase inhibitor selectivity;Davis;Nat Biotechnol,2011

2. Population pharmacokinetic/pharmacodynamic modeling to assist dosing schedule selection for dovitinib;Wang;J Clin Pharmacol,2012

3. Dovitinib induces apoptosis and overcomes sorafenib resistance in hepatocellular carcinoma through SHP-1-mediated inhibition of STAT3;Tai;Mol Cancer Ther,2012

4. The purinome, a complex mix of drug and toxicity targets;Haystead;Curr Top Med Chem,2006

5. Nucleotide-dependent domain movement in the ATPase domain of a human type IIA DNA topoisomerase;Wei;J Biol Chem,2005

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