The discovery, complex crystal structure, and recognition mechanism of a novel natural PDE4 inhibitor from Selaginella pulvinata-Reference-Cited by-同舟云学术

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The discovery, complex crystal structure, and recognition mechanism of a novel natural PDE4 inhibitor from Selaginella pulvinata

Published:2017-04 Issue: Volume:130 Page:51-59
ISSN:0006-2952
Container-title:Biochemical Pharmacology
language:en
Short-container-title:Biochemical Pharmacology

Author:

Huang Yiyou^ORCID,Liu Xin,Wu Deyan,Tang Guihua,Lai Zengwei,Zheng Xuehua,Yin Sheng,Luo Hai-Bin

Funder

Natural Science Foundation of China

National High Technology Research and Development Program of China

Natural Science Foundation of Guangdong Province

Guangdong Province Higher Vocational Colleges & Schools Pearl River Scholar Funded Scheme

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference43 articles.

1. Cyclic nucleotide phosphodiesterases: molecular regulation to clinical use;Bender;Pharmacol. Rev.,2006

2. Biochemistry and physiology of cyclic nucleotide phosphodiesterases: essential components in cyclic nucleotide signaling;Conti;Annu. Rev. Biochem.,2007

3. Cyclic nucleotide phosphodiesterase (PDE) isozymes as targets of the intracellular signalling network: benefits of PDE inhibitors in various diseases and perspectives for future therapeutic developments;Keravis;Br. J. Pharmacol.,2012

4. Design of phosphodiesterase 4D (PDE4D) allosteric modulators for enhancing cognition with improved safety;Burgin;Nat. Biotechnol.,2010

5. Keynote review: phosphodiesterase-4 as a therapeutic target;Houslay;Drug Discov. Today,2005

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1. Discovery and Optimization of 4-(Imidazo[1,2-a]pyrimidin-3-yl)thiazol-2-amine Derivatives as Novel Phosphodiesterase 4 Inhibitors;2024-08-30

2. Structural optimization of Moracin M as novel selective phosphodiesterase 4 inhibitors for the treatment of idiopathic pulmonary fibrosis;Bioorganic Chemistry;2024-08

3. Selagibenzophenone B and Its Derivatives: SelB-1, a Dual Topoisomerase I/II Inhibitor Identified through In Vitro and In Silico Analyses;ACS Bio & Med Chem Au;2024-07-26

4. PDE4D: A Multipurpose Pharmacological Target;International Journal of Molecular Sciences;2024-07-24

5. Discovery of amentoflavone as a natural PDE4 inhibitor with anti-fibrotic effects;Chinese Chemical Letters;2024-05

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