Novel bile acid derivatives (BANBs) with cytostatic activity obtained by conjugation of their side chain with nitrogenated bases

Author:

Vallejo Marta,Castro Maria A.,Medarde Manuel,Macias Rocio I.R.,Romero Marta R.,El-Mir Mohamad Y.,Monte Maria J.,Briz Oscar,Serrano Maria A.,Marin Jose J.G.

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference36 articles.

1. Liver targeting of cisplatin-derived cytostatic drugs (Bamets) by coupling to bile acids health;Marin,2001

2. Carriers involved in targeting the cytostatic bile acid-cisplatin derivatives cis-diammine-chloro-cholylglycinate-platinum(II) and cis-diammine-bisursodeoxycholate-platinum(II) toward liver cells;Briz;Mol Pharmacol,2002

3. Liver organotropism and biotransformation of a novel platinum-ursodeoxycholate derivative, Bamet-UD2, with enhanced antitumour activity;Larena;J Drug Target,2001

4. Transport and biotransformation of the new cytostatic complex cis-diammineplatinum(II)-chlorocholylglycinate (Bamet-R2) by the rat liver;Macias;J Lipid Res,1998

5. Low in vivo toxicity of a novel cisplatin-ursodeoxycholic derivative (Bamet-UD2) with enhanced cytostatic activity versus liver tumors;Dominguez;J Pharmacol Exp Ther,2001

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