Protection against lipopolysaccharide-induced sepsis and inhibition of interleukin-1β and prostaglandin E2 synthesis by silymarin

Author:

Kang Jong Soon,Jeon Young Jin,Park Song-Kyu,Yang Kyu-Hwan,Kim Hwan Mook

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference35 articles.

1. Biochemical bases of the pharmacological action of the flavonoid silymarin and of its structural isomer silibinin;Valenzuela;Biol. Res.,1994

2. Lipid peroxidation and irreversible damage in the rat hepatocyte model. Protection by the silybin-phospholipid complex IdB 1016;Carini;Biochem. Pharmacol.,1992

3. Protection against microcystin-LR-induced hepatotoxicity by silymarin: biochemistry, histopathology, and lethality;Mereish;Pharm. Res.,1991

4. Anticarcinogenic effect of a flavonoid antioxidant, silymarin, in human breast cancer cells MDA-MB 468: induction of G1 arrest through an increase in Cip1/p21 concomitant with a decrease in kinase activity of cyclin-dependent kinases and associated cyclins;Zi;Clin. Cancer Res.,1998

5. Inhibition of human carcinoma cell growth and DNA synthesis by silibinin, an active constituent of milk thistle: comparison with silymarin;Bhatia;Cancer Lett.,1999

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