Short-term rapamycin treatment increases life span and attenuates aortic aneurysm in a murine model of Marfan-Syndrome-Reference-Cited by-同舟云学术

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Short-term rapamycin treatment increases life span and attenuates aortic aneurysm in a murine model of Marfan-Syndrome

Published:2022-11 Issue: Volume:205 Page:115280
ISSN:0006-2952
Container-title:Biochemical Pharmacology
language:en
Short-container-title:Biochemical Pharmacology

Author:

Zaradzki M.,Mohr F.,Lont S.,Soethoff J.,Remes A.,Arif R.,Müller O.J.,Karck M.,Hecker M.,Wagner A.H.

Funder

Deutsche Forschungsgemeinschaft

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference52 articles.

1. The molecular genetics of Marfan syndrome and related disorders;Robinson;J. Med. Genet.,2006

2. Marfan syndrome: a therapeutic challenge for long-term care;Wagner;Biochem. Pharmacol.,2019

3. Rapamycin attenuates a murine model of thoracic aortic aneurysm by downregulating the miR-126-3p mediated activation of MAPK/ERK signalling pathway;Liu;Biochem. Biophys. Res. Commun.,2019

4. The multifaceted role of mTOR in cellular stress responses;Proud;DNA Repair (Amst),2004

5. Diverse signaling mechanisms of mTOR complexes: mTORC1 and mTORC2 in forming a formidable relationship;Jhanwar-Uniyal;Adv. Biol. Regul.,2019

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. An exploration of alternative therapeutic targets for aortic disease in Marfan syndrome;Drug Discovery Today;2024-07

2. Altered Integrin Signaling in Thoracic Aortopathy;Arteriosclerosis, Thrombosis, and Vascular Biology;2023-07

3. Targeting the biology of aging with mTOR inhibitors;Nature Aging;2023-05-04

4. Targeting Vascular Smooth Muscle Cell Senescence: A Novel Strategy for Vascular Diseases;Journal of Cardiovascular Translational Research;2023-03-27

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