A comparison of the cyclooxygenase inhibitor-NO donors (CINOD), NMI-1182 and AZD3582, using in vitro biochemical and pharmacological methods

Author:

Young Delano V.,Cochran Edward D.,Dhawan Vijay,Earl Richard A.,Ellis James L.,Garvey David S.,Janero David R.,Khanapure Subhash P.,Letts L. Gordon,Melim Terry L.,Murty Madhavi G.,Shumway Matthew J.,Wey Shiow-Jyi,Zemtseva Irina S.,Selig William M.

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference34 articles.

1. The Coxibs, selective inhibitors of cyclooxygenase-2;FitzGerald;N Engl J Med,2001

2. Cyclooxygenase-2: its rich diversity of roles and possible application of its selective inhibitors;Katori;Inflamm Res,2000

3. Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: identification of 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1h-pyrazol-1-yl]benzenesulfonamide (SC-58635 Celecoxib);Penning;J Med Chem,1997

4. Rofecoxib [Vioxx, MK-0966; 4-(4′-methylsulfonylphenyl)-3-phenyl-2-(5h)-furanone]: a potent and orally active cyclooxygenase-2 inhibitor. Pharmacological and biochemical profiles;Chan;J Pharmacol Exp Ther,1999

5. 4-[5-Methyl-3-phenylisoxazol-4-yl]-benzenesulfonamide Valdecoxib: a potent and selective inhibitor of COX-2;Talley;J Med Chem,2000

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