The mechanism causing the difference in kinetic properties between rat CYP2D4 and human CYP2D6 in the oxidation of dextromethorphan and bufuralol

Author:

Narimatsu Shizuo,Kazamori Daichi,Masuda Kazufumi,Katsu Takashi,Funae Yoshihiko,Naito Shinsaku,Nakura Hironori,Yamano Shigeru,Hanioka Nobumitsu

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference28 articles.

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3. Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians;Shimada;J Pharmacol Exp Ther,1994

4. Pharmacogenomics: translating functional genomics into rational therapeutics;Evans;Science,1999

5. Pharmacogenetics of cytochrome P450 and its applications in drug therapy: the past, present and future;Ingelman-Sundberg;Trends Pharmacol Sci,2004

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