The nuclear receptors pregnane X receptor and constitutive androstane receptor contribute to the impact of fipronil on hepatic gene expression linked to thyroid hormone metabolism-Reference-Cited by-同舟云学术

The nuclear receptors pregnane X receptor and constitutive androstane receptor contribute to the impact of fipronil on hepatic gene expression linked to thyroid hormone metabolism

Published:2013-10 Issue:7 Volume:86 Page:997-1039
ISSN:0006-2952
Container-title:Biochemical Pharmacology
language:en
Short-container-title:Biochemical Pharmacology

Author:

Roques Béatrice B.,Leghait Julien,Lacroix Marlène Z.,Lasserre Frédéric,Pineau Thierry,Viguié Catherine,Martin Pascal G.P.

Funder

Région Midi-Pyrénées

French Ministry of Ecology and Sustainable Development

Ministère de l’Enseignement Supérieur et de la Recherche

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

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4. Fipronil-induced disruption of thyroid function in rats is mediated by increased total and free thyroxine clearances concomitantly to increased activity of hepatic enzymes;Leghait;Toxicology,2009

5. CYP450-dependent biotransformation of the insecticide fipronil into fipronil sulfone can mediate fipronil-induced thyroid disruption in rats;Roques;Toxicol Sci,2012

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