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Canagliflozin inhibits p-gp function and early autophagy and improves the sensitivity to the antitumor effect of doxorubicin

  • Published:2020-05 Issue: Volume:175 Page:113856
  • ISSN:0006-2952
  • Container-title:Biochemical Pharmacology
  • language:en
  • Short-container-title:Biochemical Pharmacology

Author:

Zhong Jin,Sun Pengbo,Xu Naihan,Liao Meijian,Xu Chenke,Ding Yipei,Cai Jin,Zhang Yaou,Xie Weidong

Funder

State Key Laboratory of Chemical Oncogenomics, China

Shenzhen Science and Technology Innovation Committee

National Natural Science Foundation of China

Natural Science Foundation of Guangdong Province

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference25 articles.

1. Cancer statistics in China, 2015;Chen;CA: A Cancer J.,2016

2. Overcoming ABC transporter-mediated multidrug resistance: molecular mechanisms and novel therapeutic drug strategies;Li;Drug Resist. Updates,2016

3. The different mechanisms of cancer drug resistance: a brief review;Mansoori;Adv. Pharm. Bull.,2017

4. P-glycoprotein–implications of metabolism of neoplastic cells and cancer therapy;Breier;Curr. Cancer Drug Targets,2005

5. Targeting autophagy in cancer;Levy;Nat. Rev. Cancer,2017

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