The combi-targeting concept: intracellular fragmentation of the binary epidermal growth factor (EGFR)/DNA targeting “combi-triazene” SMA41

Author:

Matheson Stephanie L,Brahimi Fouad,Jean-Claude Bertrand J

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference19 articles.

1. Constitutive overexpression of cyclin D1 in human breast epithelial cells does not prevent G1 arrest by deprivation of epidermal growth factor;Chou;Breast Cancer Res. Treat,1999

2. Epidermal growth factor receptor activation in androgen-independent but not androgen-dependent growth of human prostate carcinoma cells;Sherwood;Br. J. Cancer,1999

3. Activated extracellular signal-related kinases: association with epidermal growth factor receptor/transforming growth factor-α expression in head and neck squamous carcinoma and inhibition by anti-epidermal growth factor receptor treatments;Albanell;Cancer Res.,2001

4. New therapeutic agents targeting the epidermal growth factor receptor;Baselga;J. Clin. Oncol.,2000

5. Phase I safety, pharmacokinetic, and pharmacodynamic trial of ZD1839, a selective oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with five selected solid tumor types;Baselga;J. Clin. Oncol.,2002

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