Nimesulide binding site in the B0AT1 (SLC6A19) amino acid transporter. Mechanism of inhibition revealed by proteoliposome transport assay and molecular modelling-Reference-Cited by-同舟云学术

Nimesulide binding site in the B0AT1 (SLC6A19) amino acid transporter. Mechanism of inhibition revealed by proteoliposome transport assay and molecular modelling

Published:2014-06 Issue:3 Volume:89 Page:422-430
ISSN:0006-2952
Container-title:Biochemical Pharmacology
language:en
Short-container-title:Biochemical Pharmacology

Author:

Pochini Lorena,Seidita Angela,Sensi Cristina,Scalise Mariafrancesca,Eberini Ivano,Indiveri Cesare

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference38 articles.

1. Hartnup disorder is caused by mutations in the gene encoding the neutral amino acid transporter SLC6A19;Seow;Nat Genet,2004

2. Mutations in SLC6A19, encoding B0AT1, cause Hartnup disorder;Kleta;Nat Genet,2004

3. Homozygosity mapping to chromosome 5p15 of a gene responsible for Hartnup disorder;Nozaki;Biochem Biophys Res Commun,2001

4. Molecular cloning of mouse amino acid transport system B0, a neutral amino acid transporter related to Hartnup disorder;Broer;J Biol Chem,2004

5. The role of the neutral amino acid transporter B0AT1 (SLC6A19) in Hartnup disorder and protein nutrition;Broer;IUBMB Life,2009

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