Systematic analysis of factors influencing observations of biased agonism at the mu-opioid receptor-Reference-Cited by-同舟云学术

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Systematic analysis of factors influencing observations of biased agonism at the mu-opioid receptor

Published:2016-08 Issue: Volume:113 Page:70-87
ISSN:0006-2952
Container-title:Biochemical Pharmacology
language:en
Short-container-title:Biochemical Pharmacology

Author:

Thompson Georgina L.,Lane J. Robert,Coudrat Thomas,Sexton Patrick M.,Christopoulos Arthur,Canals Meritxell

Funder

Australian Commonwealth Government Department of Defence

NHMRC

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference60 articles.

1. Functional selectivity and classical concepts of quantitative pharmacology;Urban;J. Pharmacol. Exp. Ther.,2007

2. Signalling bias in new drug discovery: detection, quantification and therapeutic impact;Kenakin;Nat. Rev. Drug. Discov.,2013

3. A simple method for quantifying functional selectivity and agonist bias;Kenakin;ACS Chem. Neurosci.,2012

4. Operational models of pharmacological agonism;Black;Proc. R. Soc. Lond. B. Biol. Sci.,1983

5. Identification of novel functionally selective kappa-opioid receptor scaffolds;White;Mol. Pharmacol.,2014

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