Kinetic mechanism of time-dependent inhibition of CYP2D6 by 3,4-methylenedioxymethamphetamine (MDMA): Functional heterogeneity of the enzyme and the reversibility of its inactivation-Reference-Cited by-同舟云学术

Kinetic mechanism of time-dependent inhibition of CYP2D6 by 3,4-methylenedioxymethamphetamine (MDMA): Functional heterogeneity of the enzyme and the reversibility of its inactivation

Published:2018-10 Issue: Volume:156 Page:86-98
ISSN:0006-2952
Container-title:Biochemical Pharmacology
language:en
Short-container-title:Biochemical Pharmacology

Author:

Rodgers John T.,Davydova Nadezhda Y.,Paragas Erickson M.,Jones Jeffrey P.,Davydov Dmitri R.

Funder

NIH

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference65 articles.

1. Inhibition of cytochrome P450 enzymes;de Montellano,1995

2. Mechanism-based inactivation (MBI) of cytochrome P450 enzymes: structure-activity relationships and discovery strategies to mitigate drug-drug interaction risks;Orr;J. Med. Chem.,2012

3. Mechanism-based inactivation of human cytochrome P450 enzymes and the prediction of drug-drug interactions;Obach;Drug Metab. Disp.,2007

4. Time-dependent CYP inhibition;Riley;Expert Opin. Drug Metab. Toxicol.,2007

5. CYP3A time-dependent inhibition risk assessment validated with 400 reference drugs;Zimmerlin;Drug Metab. Disp.,2011

Cited by 15 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Post mortem chiral analysis of MDMA and MDA in human blood and hair;Forensic Science International;2024-09

2. Enzyme-mediated drug-drug interactions: a review of in vivo and in vitro methodologies, regulatory guidance, and translation to the clinic;Drug Metabolism Reviews;2024-07-26

3. Hepatic injury and hepatic failure adverse events in 3,4-methylenedioxymethamphetamine users reported to the FDA Adverse Event Reporting System;Frontiers in Psychiatry;2024-06-18

4. Concomitant medications associated with ischemic, hypertensive, and arrhythmic events in MDMA users in FDA adverse event reporting system;Frontiers in Psychiatry;2023-05-18

5. Reported Cases of Serotonin Syndrome in MDMA Users in FAERS Database;Frontiers in Psychiatry;2022-01-24