Minor structural modifications to alchemix influence mechanism of action and pharmacological activity-Reference-Cited by-同舟云学术

Minor structural modifications to alchemix influence mechanism of action and pharmacological activity

Published:2012-06 Issue:11 Volume:83 Page:1514-1522
ISSN:0006-2952
Container-title:Biochemical Pharmacology
language:en
Short-container-title:Biochemical Pharmacology

Author:

Abdallah Qasem M.A.,Phillips Roger M.,Johansson Fredrik,Helleday Thomas,Cosentino Laura,Abdel-Rahman Hamdy,Etzad Jasarat,Wheelhouse Richard T.,Kiakos Konstantinos,Bingham John P.,Hartley John A.,Patterson Laurence H.,Pors Klaus

Funder

Yorkshire Cancer Research (Program Grant)

White Rose Health Innovation Partnership

Cancer Research UK

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference40 articles.

1. Anthracycline and anthraquinone anticancer agents: current status and recent developments;Lown;Pharmacol Ther,1993

2. Antitumor agents. 1. 1,4-Bis[(aminoalkyl)amino]-9,10-anthracenediones;Murdock;J Med Chem,1979

3. Experimental antitumor activity of aminoanthraquinones;Johnson;Cancer Treat Rep,1979

4. Structural modification study of mitoxantrone (DHAQ). Chloro-substituted mono- and bis[(aminoalkyl)amino]anthraquinones;Zee-Cheng;J Med Chem,1987

5. Synthesis and antitumor activities of unsymmetrically substituted 1,4-bis[(aminoalkyl)amino]anthracene-9,10-diones and related systems;Krapcho;J Med Chem,1986

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