Metabolism of short-chain ceramide by human cancer cells—Implications for therapeutic approaches

Author:

Chapman Jacqueline V.,Gouazé-Andersson Valérie,Messner Maria C.,Flowers Margaret,Karimi Ramin,Kester Mark,Barth Brian M.,Liu Xin,Liu Yong-Yu,Giuliano Armando E.,Cabot Myles C.

Funder

USPHS

the Association for Breast and Prostate Cancer Studies (Los Angeles)

the Fashion Footwear Association of New York Charitable Foundation (New York, NY)

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference44 articles.

1. Accumulation of glucosylceramides in multidrug-resistant cancer cells;Lavie;J Biol Chem,1996

2. Glucosylceramide: a marker for multiple-drug resistant cancers;Lucci;Anticancer Res,1998

3. A role for ceramide in driving cancer cell resistance to doxorubicin;Liu;FASEB J,2008

4. Differential expression of sphingolipids in MRP1 overexpressing HT29 cells;Kok;Int J Cancer,2000

5. Overexpression of glucosylceramide synthase and P-glycoprotein in cancer cells selected for resistance to natural product chemotherapy;Gouaze;Mol Cancer Ther,2004

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