Inhibition of hepatic carnitine palmitoyl-transferase I (CPT IA) by valproyl-CoA as a possible mechanism of valproate-induced steatosis-Reference-Cited by-同舟云学术

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Inhibition of hepatic carnitine palmitoyl-transferase I (CPT IA) by valproyl-CoA as a possible mechanism of valproate-induced steatosis

Published:2010-03 Issue:5 Volume:79 Page:792-799
ISSN:0006-2952
Container-title:Biochemical Pharmacology
language:en
Short-container-title:Biochemical Pharmacology

Author:

Aires Cátia C.P.,IJlst Lodewijk,Stet Femke,Prip-Buus Carina,de Almeida Isabel Tavares,Duran Marinus,Wanders Ronald J.A.,Silva Margarida F.B.

Funder

Fundação para a Ciência e a Tecnologia (FCT), Lisboa, Portugal

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference40 articles.

1. The mitochondrial intermembrane loop region of rat carnitine palmitoyltransferase 1A is a major determinant of its malonyl-CoA sensitivity;Borthwick;J Biol Chem,2006

2. Demonstration of N- and C-terminal domain intramolecular interactions in rat liver carnitine palmitoyltransferase 1 that determine its degree of malonyl-CoA sensitivity;Faye;Biochem J,2005

3. Carnitine palmitoyltransferase I: the site of inhibition of hepatic fatty acid oxidation by malonyl-CoA;McGarry;J Biol Chem,1978

4. Inhibition of hypothalamic fatty acid synthase triggers rapid activation of fatty acid oxidation in skeletal muscle;Cha;Proc Natl Acad Sci USA,2005

5. Role of malonyl-CoA in heart disease and the hypothalamic control of obesity;Folmes;Cardiovasc Res,2007

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