Metabolic activation of drugs by cytochrome P450 enzymes: Biochemical insights into mechanism-based inactivation by fibroblast growth factor receptor inhibitors and chemical approaches to attenuate reactive metabolite formation
Author:
Funder
Ministry of Education - Singapore
National University of Singapore
Publisher
Elsevier BV
Subject
Pharmacology,Biochemistry
Reference113 articles.
1. Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients;Pirmohamed;BMJ.,2004
2. Incidence of adverse drug reactions in paediatric in/out-patients: a systematic review and meta-analysis of prospective studies;Impicciatore;Br. J. Clin. Pharmacol.,2001
3. Clinical and economic burden of adverse drug reactions;Sultana;J. Pharmacol. Pharmacother.,2013
4. Adverse drug event monitoring at the food and drug administration: Your report can make a difference;Ahmad;J. Gen. Intern. Med.,2003
5. Can the pharmaceutical industry reduce attrition rates?;Kola;Nat. Rev. Drug Discov.,2004
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