A kinase inhibitor screen reveals MEK1/2 as a novel therapeutic target to antagonize IGF1R-mediated antiestrogen resistance in ERα-positive luminal breast cancer-Reference-Cited by-同舟云学术

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A kinase inhibitor screen reveals MEK1/2 as a novel therapeutic target to antagonize IGF1R-mediated antiestrogen resistance in ERα-positive luminal breast cancer

Published:2022-10 Issue: Volume:204 Page:115233
ISSN:0006-2952
Container-title:Biochemical Pharmacology
language:en
Short-container-title:Biochemical Pharmacology

Author:

Wester L.,Venneker S.,Hazenoot M.,Pont C.,Koedoot E.,Timmermans A.M.,Martens J.W.M.,Jansen M.P.H.M.,Kockx C.E.M.,van IJcken W.F.J.,Meerman J.H.N.,Zhang Y.,van de Water B.

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference79 articles.

1. Estrogen receptor alpha phosphorylation and its functional impact in human breast cancer;Anbalagan;Mol Cell Endocrinol,2015

2. Anti-oestrogen therapy for breast cancer: a trial of tamoxifen at two dose levels;Ward;Br Med J,1973

3. Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials;The Lancet,2005

4. Endocrine therapy resistance in estrogen receptor (ER)-positive breast cancer;De Marchi;Drug Discov Today,2016

5. ESR1 mutations - a mechanism for acquired endocrine resistance in breast cancer;Jeselsohn;Nat Rev Clin Oncol,2015

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