Spontaneous apoptosis, necrosis, energy status, glutathione levels and biotransformation capacities of isolated rat hepatocytes in suspension: Effect of the incubation medium

Author:

Elaut Greetje,Vanhaecke Tamara,Heyden Yvan Vander,Rogiers Vera

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference50 articles.

1. Oxidative stress, antioxidant defences, and damage removal, repair, and replacement systems;Davies;Life,2000

2. Practical aspects of in vitro biotransformation studies during early drug development;Elaut,2002

3. Proposal for a regulation of the European Parliament and of the Council concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH), establishing a European Chemicals Agency and amending Directive 1999/45/EC and Regulation (EC) (on persistent organic pollutants). (COM 2003 0644 (03)). http://europa.eu.int/eur-lex/com/pdf/2003/com2003_0644en.html. (accessed 09/11/2004).

4. Use of isolated and cultured hepatocytes for xenobiotic metabolism and cytotoxicity studies;Guillouzo,1986

5. The potential use of cultured hepatocytes in predicting the hepatotoxicity of xenobiotics;Gomez-Lechon;Xenobiotica,1988

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