Downstream effect profiles discern different mechanisms of integrin αLβ2 inhibition-Reference-Cited by-同舟云学术

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Downstream effect profiles discern different mechanisms of integrin αLβ2 inhibition

Published:2016-11 Issue: Volume:119 Page:42-55
ISSN:0006-2952
Container-title:Biochemical Pharmacology
language:en
Short-container-title:Biochemical Pharmacology

Author:

Mancuso Riccardo V.,Welzenbach Karl,Steinberger Peter,Krähenbühl Stephan,Weitz-Schmidt Gabriele

Funder

Swiss Commission of Technology and Innovation

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference58 articles.

1. Structural basis of integrin regulation and signalling;Luo;Annu. Rev. Immunol.,2007

2. The insider’s guide to leukocyte integrin signalling and function;Hogg;Nat. Rev. Immunol.,2011

3. Integrins as therapeutic targets: lessons and opportunities;Cox;Nat. Rev. Drug Discovery,2010

4. Integrin-based therapeutics: biological basis, clinical use and new drugs;Ley;Rev. Drug Discovery,2016

5. Therapeutic integrin inhibition: allosteric and activation-specific inhibition strategies may surpass the initial ligand-mimetic strategies;Ahrens;Thromb. Haemost.,2008

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2. Decrypting Integrins by Mixed-Solvent Molecular Dynamics Simulations;Journal of Chemical Information and Modeling;2023-06-13

3. Allosteric targeting resolves limitations of earlier LFA-1 directed modalities;Biochemical Pharmacology;2023-05

4. Anti‐αLβ2 antibodies reveal novel endocytotic cross‐modulatory functionality;British Journal of Pharmacology;2020-03-09

5. Can Integrin Agonists Have Cards to Play against Cancer? A Literature Survey of Small Molecules Integrin Activators;Cancers;2017-07-05

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