Involvement of basic amino acid residues in transmembrane regions 6 and 7 in agonist and antagonist recognition of the human platelet P2Y12-receptor

Author:

Hoffmann Kristina,Sixel Uta,Di Pasquale Francesca,von Kügelgen Ivar

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference32 articles.

1. Identification of the platelet ADP receptor targeted by antithrombotic drugs;Hollopeter;Nature,2001

2. Molecular cloning of the platelet P2TAC ADP receptor: pharmacological comparison with another ADP receptor, the P2Y1 receptor;Takasaki;Mol Pharmacol,2001

3. ADP is the cognate ligand for the orphan G protein-coupled receptor SP1999;Zhang;J Biol Chem,2001

4. Central role of the P2Y12 receptor in platelet activation;Dorsam;J Clin Invest,2004

5. P2y12, a new platelet ADP receptor, target of clopidogrel;Savi;Biochem Biophys Res Commun,2001

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